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Precision medicine

Genomics & pharmacogenomics

CPIC-graded PGx alerts at the point of prescribing, NGS panel review, and variant interpretation linked to the chart.

PGx results on file
312
Active drug-gene alerts
9
Panels pending review
4
Rx changes (30d)
22

Live drug-gene interactions

  • MRN 7821 — CYP2C19 *2/*2 — poor metabolizer
    Clopidogrel → consider prasugrel (CPIC A)
    action
  • MRN 4410 — HLA-B*57:01 positive
    Abacavir contraindicated (CPIC A)
    action
  • MRN 9012 — TPMT intermediate
    Reduce azathioprine 30–70% (CPIC A)
    action
  • MRN 6601 — DPYD c.1905+1G>A heterozygous
    Reduce fluoropyrimidine 50% (CPIC A)
    action

Panel review queue

  • Hereditary cancer 84-gene · MRN 5521queued
  • Cardiac arrhythmia panel · MRN 2210queued
  • Carrier screening · MRN 7741queued
  • WES trio · MRN 8893queued

Variant evidence sources

ClinVar (NCBI)synced 6h ago
CPIC guidelinesv2026.04
PharmGKBsynced daily
OncoKBv4.21